Sato E, Williams MR, Sanford JA, Sen GL, Nakama T, Imafuku S, Gallo RL. The parathyroid hormone family member TIP39 interacts with sarco/endoplasmic reticulum Ca2+ - ATPase activity by influencing calcium homoeostasis. Exp Dermatol. 2017 Jan 17. doi: 10.1111/exd.13294. [Epub ahead of print] PMID: 28094886
Y and Sen GL. Enhanc(er)ing Skin Stem Cells. Cell Stem Cell
19, 415-17 (2016).
Li J and Sen GL. Post-Transcriptional Mechanisms Regulating Epidermal Stem and Progenitor Cell Self-Renewal and Differentiation. Journal of Investigative Dermatology 136, 746-52 (2016).
Zhang LJ, Sen GL, Ward NL, Johnston A, Chun K, Chen Y, Adase C, Sanford JA, Gao N, Chensee M, Sato E, Fritz Y, Baliwag J, Williams MR, Hata T, Gallo RL. Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury. Immunity 45, 119-30 (2016).
Mistry DS, Chen Y, Wang Y, and Sen GL. Transcriptional profiling of SNAI2 regulated genes in primary human keratinocytes. Genomics Data 4, 43-46 (2015).
Li G, Xu F, Zhu J, Krawczyk M, Zhang Y, Yuan J, Patel S, Wang Y, Lin Y, Zhang M, Cai H, Chen D, Zhang M, Cao G, Yeh E, Lin D, Su Q, Li WW, Sen GL, Afshari N, Chen S, Maas RL, Fu XD, Zhang K, Liu Y, and Ouyang H. Transcription Factor PAX6 (Paired Box 6) Controls Limbal Stem Cell Lineage in Development and Disease. Journal of Biological Chemistry 290, 20448-54 (2015).
Wang Y, Arribas-Layton M, Chen Y, Lykke-Andersen J, and Sen GL. DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways. Molecular Cell 60, 118-30 (2015).
Chen Y and Sen GL. SOX2 expression inhibits terminal epidermal differentiation. Experimental Dermatology 24, 974-6 (2015).
Li J and Sen GL. Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis. Journal of Visual Experiments 106 (2015).
Mistry DS, Chen Y,
Wang Y, Zhang K and Sen GL. SNAI2 controls the undifferentiated state of
human epidermal progenitor cells. Stem Cells 32, 3209-18
Chen, Y, Mistry D.S.,and Sen, G.L. Highly rapid and efficient conversion of human fibroblasts to keratinocyte-like cells. J Invest Dermatol. Epub ahead of print Aug. 6, 2013.
Mistry, D.S., Chen, Y., and Sen, G.L. Progenitor function in self-renewing human epidermis is maintained by the exosome. Cell Stem Cell 11, 127-35 (2012).
Sen, G.L., Boxer, L.D., Webster, D.E., Bussat, R.T., Qu, K., Zarnegar, B.J., Johnston, D., Siprashvili, Z.,and Khavari, P.A. ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation. Dev Cell 22, 669-77 (2012).
Muehleisen, B., Bikle, D.D., Aquilera, C., Burton, D.W., Sen, G.L., Deftos, L.J., and Gallo, R.L. PTH/PTHrP and Vitamin D control antimicrobial peptide expression and susceptibility to bacterial skin infection. Sci Trans Med. 4, 135-66 (2012).
Zarnegar, B.J., Webster, D.E., Lopez-Pajares, V., Vander Stoep Hunt, B., Qu, K., Yan, K.J., Berk, D.R., Sen, G.L., and Khavari, P.A. Genomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63. AM J Hum Genet. (2012).
Sen, G.L. Remembering one’s identity: the epigenetic basis of stem cell fate decisions. Faseb Journal. (2011 Mar 25). [Epub ahead of print]
Khavari, D.A., Sen G.L., and Rinn J.L. DNA methylation and epigenetic control of cellular differentiation. Cell Cycle 19, 3880-3 (2010).
Sen, G.L., Reuter, J.A., Zhu, L., and Khavari, P.A. DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature 463, 563-567 (2010). Comment in Stanford Report. Recommended by Faculty of 1000.
Sen, G.L., Webster D.E., Barragan, D.I., Chang H.Y., and Khavari P.A. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes and Development 22, 1865-70 (2008). Recommended by Faculty of 1000.
Zhang, F, Pomerantz, J.H., Sen, G.L., Palermo, A.T., and Blau, H.M. Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons. PNAS 104, 4395-400 (2007). *co-first authors.
Sen, G.L.& Blau, H.M. A Brief History of RNAi (The Silence of the Genes) Faseb Journal 20, 1293-9 (2006).
Sen, G.L., Wehrman, T.S., & Blau, H. M. mRNA translation is not a prerequisite for small interfering RNA-mediated mRNA cleavage. Differentiation 73, 287-293(2005).
Sen, G.L. & Blau, H. M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nature Cell Biology 7, 633-636 (2005). Comment in Nature, Nature Cell Biology, Science, and Nature Structural and Molecular Biology. Recommended by Faculty of 1000.
Sen, G.L., Wehrman, T. S., Myers, J. W. & Blau, H. M. Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nature Genetics 36, 183-189 (2004). Comment in Stanford Report and RNA. Recommended by Faculty of 1000.