Publications

Featured Publications

CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation

Sun BK, Boxer LD, Ransohoff JD, Siprashvili Z, Qu K, Lopez-Pajares V, Hollmig ST, and PA Khavari.
Genes and Development (2015)

  • Laser capture microdissection/RNA-seq of progenitor and differentiated layers of human epidermis identifies CALML5 as the most highly enriched differentiation gene
  • CALML5 knockout in xenografted human epidermis results in impaired tissue differentiation 
  • TINCR and ZNF750 are required for CALML5 induction
  • CALML5 binds stratifin (SFN) to co-control expression of differentiation genes
                  

Advances in skin grafting and treatment of cutaneous wounds

Sun BK, Siprashvili Z, and PA Khavari.
Science (2014)

  • Advances in the understanding of epidermal wound healing and skin grafting raise the promise for better treatment of skin injuries, chronic wounds, and genetic skin diseases
  • Improved understanding of stem cell biology, together with rapid advancement in genome engineering tools, are bringing the goal of true skin regeneration closer to reality

      

Publications Listing 


Cai ED, Sun BK, Chiang A, Rogers A, Bernet L, Cheng B, Teng J, Rieger KE, Sarin KY.
The Journal of investigative dermatology. 2017; 137(8):1795-1798.
PubMed [journal] PMID:28347698

Sun BK, Wang H, Kim J, Chen JK, Sun L, Zhang Y, Swetter SM.
Journal of the American Academy of Dermatology. 2016; 75(6):1263-1265.e5.
PubMed [journal] PMID: 27846954

Patient satisfaction in dermatologic care delivered by a medical-student-run free clinic.
Pyles MN, Nkansah N, Sun BK.
Journal of the American Academy of Dermatology. 2016; 74(6):1265-7.
PubMed [journal] PMID:  27185434  

CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation.
Sun BK, Boxer LD, Ransohoff JD, Siprashvili Z, Qu K, Lopez-Pajares V, Hollmig ST, Khavari PA.
Genes & development. 2015; 29(21):2225-30.
PubMed [journal] PMID:  26545810 PMCID:  PMC4647556

Advances in skin grafting and treatment of cutaneous wounds.
Sun BK, Siprashvili Z, Khavari PA.
Science (New York, N.Y.). 2014; 346(6212):941-5.
PubMed [journal] PMID:  25414301

Activating HRAS mutation in agminated Spitz nevi arising in a nevus spilus.
Sarin KY, Sun BK, Bangs CD, Cherry A, Swetter SM, Kim J, Khavari PA.
JAMA dermatology. 2013; 149(9):1077-81.
PubMed [journal] PMID:  23884457

Mosaic activating RAS mutations in nevus sebaceus and nevus sebaceus syndrome.
Sun BK, Saggini A, Sarin KY, Kim J, Benjamin L, LeBoit PE, Khavari PA.
The Journal of investigative dermatology. 2013; 133(3):824-7. NIHMSID: NIHMS407009
PubMed [journal] PMID:  23096709  PMCID:  PMC3556351

X-chromosome inactivation and skin disease.
Sun BK, Tsao H.
The Journal of investigative dermatology. 2008; 128(12):2753-9.
PubMed [journal] PMID:  18509358

Small RNAs in development and disease.
Sun BK, Tsao H.
Journal of the American Academy of Dermatology. 2008; 59(5):725-37; quiz 738-40.
PubMed [journal] PMID:  19119093

Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome.
Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT.
Science (New York, N.Y.). 2008; 322(5902):750-6. NIHMSID: NIHMS137219
PubMed [journal] PMID:  18974356  PMCID:  PMC2748911

Intersection of the RNA interference and X-inactivation pathways.
Ogawa Y, Sun BK, Lee JT.
Science (New York, N.Y.). 2008; 320(5881):1336-41. NIHMSID: HHMIMS74275
PubMed [journal] PMID:  18535243  PMCID:  PMC2584363

A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization.
Sun BK, Deaton AM, Lee JT.
Molecular cell. 2006; 21(5):617-28.
PubMed [journal] PMID:  16507360

Differential methylation of Xite and CTCF sites in Tsix mirrors the pattern of X-inactivation choice in mice.
Boumil RM, Ogawa Y, Sun BK, Huynh KD, Lee JT.
Molecular and cellular biology. 2006; 26(6):2109-17.
PubMed [journal] PMID:  16507990  PMCID:  PMC1430288

X-chromosome kiss and tell: how the Xs go their separate ways.
Anguera MC, Sun BK, Xu N, Lee JT.
Cold Spring Harbor symposia on quantitative biology. 2006; 71:429-37.
PubMed [journal] PMID:  17381325

Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays.
Hacia JG, Fan JB, Ryder O, Jin L, Edgemon K, Ghandour G, Mayer RA, Sun B, Hsie L, Robbins CM, Brody LC, Wang D, Lander ES, Lipshutz R, Fodor SP, Collins FS.
Nature genetics. 1999; 22(2):164-7.
PubMed [journal] PMID:  10369258

Strategies for mutational analysis of the large multiexon ATM gene using high-density oligonucleotide arrays.
Hacia JG, Sun B, Hunt N, Edgemon K, Mosbrook D, Robbins C, Fodor SP, Tagle DA, Collins FS.
Genome research. 1998; 8(12):1245-58.
PubMed [journal] PMID:  9872980

Two color hybridization analysis using high density oligonucleotide arrays and energy transfer dyes.
Hacia JG, Edgemon K, Sun B, Stern D, Fodor SP, Collins FS.
Nucleic acids research. 1998; 26(16):3865-6.
PubMed [journal] PMID:  9685507  PMCID:  PMC147769