Publications
Selected publications:
2019
Botulinum toxin blocks mast cells and prevents rosacea like inflammation. Choi JE, Werbel T, Wang Z, Wu CC, Yaksh TL, Di Nardo A. J Dermatol
2017
Skin microbiome and mast cells. Igawa S, Di Nardo A. J Invest Dermatol
TRPV4 Mediates Mast Cell Activation in Cathelicidin-Induced Rosacea Inflammation. Mascarenhas NL, Wang Z, Chang YL, Di Nardo A. J Invest Dermatol
Skin microbiome promotes mast cell maturation by triggering stem cell factor production in keratinocytes. Wang Z, Mascarenhas N, Eckmann L, Miyamoto Y, Sun X, Kawakami T, Di Nardo A. J
2014
Mast cells are key mediators of cathelicidin-initiated skin inflammation in rosacea. Muto Y, Wang Z, Vanderberghe M, Two A, Gallo RL, Di Nardo A J Invest Dermatol Allergy Clin Immunol
Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides. Wang Z, Lai Y, Bernard JJ, Macleod DT, Cogen AL, Moss B, Di Nardo A J Immunol
2010
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons. Gregorio J, Meller S, Conrad C, Di Nardo A, Homey B, Lauerma A, Arai N, Gallo RL, Digiovanni J, Gilliet M J Exp Med
Immunotherapy for melanoma: current status and perspectives. Alexandrescu DT, Ichim TE, Riordan NH, Marincola FM, Di Nardo A, Kabigting FD, Dasanu CA J Immunother
Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections. Lai Y, Cogen AL, Radek KA, Park HJ, Macleod DT, Leichtle A, Ryan AF, Di Nardo A, Gallo RL J Invest Dermatol
2009
Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Lai Y, Di Nardo A, Nakatsuji T, Leichtle A, Yang Y, Cogen AL, Wu ZR, Hooper LV, Schmidt RR, von Aulock S, Radek KA, Huang CM, Ryan AF, Gallo RL Nat Med
Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37. Park HJ, Cho DH, Kim HJ, Lee JY, Cho BK, Bang SI, Song SY, Yamasaki K, Di Nardo A, Gallo RL J Invest Dermatol
2008
Mast cell cathelicidin antimicrobial peptide prevents invasive group A Streptococcus infection of the skin. Di Nardo A, Yamasaki K, Dorschner RA, Lai Y, Gallo RL J Immunol
2007
Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Yamasaki K, Di Nardo A, Bardan A, Murakami M, Ohtake T, Coda A, Dorschner RA, Bonnart C, Descargues P, Hovnanian A, Morhenn VB, Gallo RL Nat Med
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on toll-like receptor 4, cd44, and md-2. Taylor KR, Yamasaki K, Radek KA, Di Nardo A, Goodarzi H, Golenbock D, Beutler B, Gallo RL Journal of Biological Chemistry
Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization. Di Nardo A, Braff MH, Taylor KR, Na C, Granstein RD, McInturff JE, Krutzik S, Modlin RL, Gallo RL J Immunol
2005
Augmentation of cutaneous immune responses by ATP gamma S: purinergic agonists define a novel class of immunologic adjuvants. Granstein RD, Ding W, Huang J, Holzer A, Gallo RL, Di Nardo A, Wagner JA J Immunol
Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities. Braff MH, Hawkins MA, Di Nardo A, Lopez-Garcia B, Howell MD, Wong C, Lin K, Streib JE, Dorschner R, Leung DY, Gallo RL J Immunol
Keratinocytes store the antimicrobial peptide cathelicidin in lamellar bodies. Braff MH, Di Nardo A, Gallo RL J Invest Dermatol
2003
Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide. Di Nardo A, Vitiello A, Gallo RL J Immunol